your microbiota are primed at birth, then over life they change at each stage of development, around 6, around 13, around 26, around 40 and later in life, they impact your microbiome which effects the way you feel profoundly as well as the function of your immune system, the clinical research is out there to support this. http://www.nature.com/articles/srep23075
ultimately I believe that artificial enzymes will unlock the secret to eternal life, I do not think I will be around to see that, yes, you can certainly 'set yourself up for success' by understanding nutrition and trying to make sure the chemistry set that is your body gets the right access to the stuff it needs to operate your biochemistry, which has a large influence over physical and mental well being.
"Resveratrol is a stilbenoid, commonly found in grapes and in the roots of the Japanese Knotweed during stress and bacterial or fungial infection. In mouse and rat experiments, resveratrol has been shown to play a role in telomere lengthening, telomerase activity enhancement, blood sugar-lowering, inhibition of platelet aggregation, promotion of vasodilation by enhancing the production of NO and have anti-inflammatory properties."