Additionally, I found Gmail will sometimes deny legitimate E-mail as "spam" as it comes in, before it even reaches your Spam folder. I tested this for a week or so by forwarding my personal E-mail from my mail server to my address at Gmail and checking my server logs. This was one of the things that finally pushed me over to self-hosting. Mail does not get lost with Spamassassin if it's set up to deliver spam into a separate folder. As long as the mail passes the trivial SPF, DKIM, etc. checks, it will at least get to my junk folder.
False positives are a nightmare and if you have to check the spam folder then the spam filter does more harm than good.
That is also my experience with SA.