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I've got you beat; neither SSRIs nor gabapentin nor any other of a variety of on- and off-label meds worked for me.

Despite that I don't think it's a good idea to recommend or disrecommend any specific drug; it is very much a biochemical roll of the dice as to whether a med will work on a given individual and the odds aren't even particularly good. My suggestion to the depressed is to try as many as you can withstand to increase your odds of finding something that works, with the understanding you might be among the unlucky ones that nothing works on.



>Despite that I don't think it's a good idea to recommend or disrecommend any specific drug; it is very much a biochemical roll of the dice as to whether a med will work on a given individual and the odds aren't even particularly good.

Since many drugs seem to affect different people differently, it seems we really need to work on understanding how drugs affect people differently based on their genetics. This is similar to, for instance, how some people think cilantro tastes like soap, because of a gene mutation. I think there isn't nearly enough attention being paid to this, and it's making the field of psychiatry look like various drugs are no better than placebo, when it's much more likely that some drugs work great for some people, but terribly or not at all for others, so right now it's a crap-shoot when instead we should be figuring out what will actually work for certain people based on their genetics instead of shooting in the dark.




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