Sure, but the previous iterations (like Strix in the non-halo form) and similar AMD laptop chips are popular with numerous SFFs from the likes of ASUS, ASRock, Gigabyte, Beelink, Minisforum, GMKtex, Lenovo, and many others.
I've heard similar rumors of similar SFFs from framework, system76, and similar VARs.
The Strix Halo does seem pretty compelling for those that want less volume, power, and money than a discrete GPU. I'd love a small SFF with either 128GB ram (some parts will have the ram in the package)) or two CUDIMM slots.
Generally SFFs use laptop parts, but tend to be out a few months later than the equivalent laptops.